The therapeutic application of endoscopic ultrasound (EUS) has become increasingly prevalent in clinical practice. Beyond the management of peripancreatic fluid collections, EUS-guided biliary drainage (EUS-BD) and the treatment of malignant gastric outlet obstruction have become valuable alternatives to traditional surgical or percutaneous approaches. Additionally, EUS-guided tumor ablation, particularly for pancreatic neuroendocrine tumors (PNET) and cystic lesions, has emerged as a promising minimally invasive option. This article provides a comprehensive overview of recent advancements and clinical outcomes in these areas, highlighting the evolving role of EUS as both a first-line intervention and a viable salvage therapy in complex cases.

Home parenteral nutrition (HPN) is the provision of long-term infusion treatment in a family setting. In this paper, I summarize our knowledge of home parenteral nutrition for children. I list the diagnoses of patients infused at home in Hungary, the complications and results of this treatment. I detail the conditions for this type of infusion treatment, the tasks of parents and the hospital department providing the background, the difficulties, the tasks that have already been solved and those that need to be solved. Overall, this is a rarely but increasingly widely used therapeutic method, with the help of which we can cure patients or ensure a good quality of life for years, who previously had to stay in hospital for months or years.

Crohn's disease occurs in the upper gastrointestinal tract in 0.5-4% of symptomatic adult patients. Involve­ment of the esophagus, stomach, or duodenum usually occurs simultaneously with involvement of the lower tract. The diagnosis is based on endoscopic, histological and radiological evaluation. Aphthoid or longitudinal ulcers, strictures and fistulas all raise the suspicion of Crohn's disease. Histologically, the presence of a chronic inflammatory process, mainly the predominance of lymphoplasmacytic cells, as well as active focal gastritis indicate Crohn's disease, epithelioid granuloma is rarely detected. During treatment, in addition to proton pump inhibitors, corticosteroids, immunomodulators and biological therapy are used, depending on the severity of the disease.